Multi-panel overview of stem cell therapies for neurological disorders, with preclinical and clinical findings for each condition

Stem Cell Therapies for Neurological Disorders: A Ten-Disease Overview

Type: Personal project
Based on: Stem cell therapies for neurological disorders: current progress, challenges and future perspectives by Ramyar Rahimi Darehbagh et al.
Field: Regenerative neuroscience / cell therapy
Figure type: Multi-panel review summary

Why I made it

I enjoyed reading this review and wanted to test a question that comes up with almost every review figure: how much of a broad paper can fit into one image without losing the reader? The review covers ten neurological conditions, four stem cell types, and both animal and human evidence.

Hand-drawn layout sketch for a stem cell therapy overview, with a grid of panels for different neurological disorders
The initial sketch

The challenge

Ten diseases is a lot of panels. If each one had its own layout, the reader would have to relearn the figure ten times. The figure also had to separate preclinical results from clinical trial results, because the two often disagree.

My approach

One template for every disease: each panel has the same structure: a simple anatomical icon, then “Preclinical studies” and “Clinical trials” with the cell type and its effect. Once the reader understands one panel, they can read all ten.

A shared cell-type legend: iPSCs, ESCs, MSCs, and NSCs are drawn once at the top, so the panels can refer to them by name without repeating icons.

Arrows instead of sentences: ↑ and ↓ show improvement or reduction, which keeps each finding to a single line.

Individual illustrated elements for the stem cell figure, including brains, a spinal cord, neurons and stem cell types, before layout
The elements designed and ready to set in place
First draft of the stem cell therapy figure with the disease panels arranged in a grid
The first draft with elements set in place

Testing the color scheme

For the second draft I tried two backgrounds side by side, a cool grey and a warm bone tone, to see which made the colored icons easier to read. The final version uses a light grey that keeps the panels calm and lets the anatomy stand out.

Second draft of the stem cell therapy figure on a dark grey background
The second draft
Alternative color version of the stem cell therapy figure on a bone-colored background
The color alternative for the draft
Multi-panel overview of stem cell therapies for neurological disorders, with preclinical and clinical findings for Alzheimer's disease, Parkinson's disease, multiple sclerosis, ALS, spinal cord injury, traumatic brain injury, epilepsy, Huntington's disease, stroke and other conditions
The final illustration

The result

A single figure that summarizes a long review in a format readers can scan disease by disease. The same template approach works for any review that compares one intervention across many conditions.

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